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MMP27 Related Area

MMP27 Related Pathways

    MMP27 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    MMP27 Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    MMP27 Summary & Protein Information

    MMP27 Background

    Cofactor: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; ; Note=Binds 4 Ca(2+) ions per subunit. {ECO:0000250};; Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; ; Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
    Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein {ECO:0000269|PubMed:24548619}. Note=Retained in the endoplasmic reticulum. {ECO:0000269|PubMed:24548619}.
    Tissue specificity: Expressed in B-cells (PubMed:14506071). Expressed in a subset of endometrial macrophages related to menstruation and in ovarian and peritoneal endometriotic lesions (at protein level)(PubMed:24810263). {ECO:0000269|PubMed:14506071, ECO:0000269|PubMed:24810263}.
    Post-translational: N-glycosylated. {ECO:0000269|PubMed:24548619}.
    Sequence similarity: Belongs to the peptidase M10A family. {ECO:0000305}.; Contains 4 hemopexin repeats. {ECO:0000305}.
    General information above from UniProt

    MMP27 Alternative Name

    MMP-27, [homo-sapiens]
    Gm180, [mus-musculus]

    MMP27 Related Studies

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