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LILRB4/CD85k/ILT3 

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LILRB4/CD85k/ILT3 Related Area

LILRB4/CD85k/ILT3 Related Pathways

    LILRB4/CD85k/ILT3 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    LILRB4/CD85k/ILT3 Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    LILRB4/CD85k/ILT3 Summary & Protein Information

    LILRB4/CD85k/ILT3 Background

    Subunit structure: Binds PTPN6 when phosphorylated.
    Domain: Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
    Subcellular location: Cell membrane {ECO:0000269|PubMed:9151699}; Single-pass type I membrane protein {ECO:0000269|PubMed:9151699}. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment.
    Tissue specificity: Detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. {ECO:0000269|PubMed:9151699, ECO:0000269|PubMed:9278324, ECO:0000269|PubMed:9548455}.
    Induction: Upon contact with CD8(+)CD28(-) alloantigen-specific T suppressor (Ts) cells.
    Sequence similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. {ECO:0000305}.
    General information above from UniProt

    LILRB4/CD85k/ILT3 Alternative Name

    LILRB4/CD85k/ILT3 Related Studies

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