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IFN-alpha / IFNA1 / IFN  Protein, Antibody, ELISA Kit, cDNA Clone

Expression host: Yeast  
12341-H08Y-20
12341-H08Y-100
20 µg 
100 µg 
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Expression host: Yeast  
50524-M08Y-20
50524-M08Y-100
20 µg 
100 µg 
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Expression host: Human Cells  
80174-R02H-20
80174-R02H-100
20 µg 
100 µg 
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Description: Active  
Expression host: Human Cells  
80174-R08H-5
80174-R08H-20
80174-R08H-100
5 µg 
20 µg 
100 µg 
Add to Cart
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IFN-alpha / IFNA1 / IFN Related Area

IFN-alpha / IFNA1 / IFN Related Pathways

    IFN-alpha / IFNA1 / IFN Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    IFN-alpha / IFNA1 / IFN Summary & Protein Information

    IFN-alpha / IFNA1 / IFN Background

    Subcellular location: Secreted {ECO:0000256|SAAS:SAAS00052390}.
    Sequence similarity: Belongs to the alpha/beta interferon family. {ECO:0000256|RuleBase:RU000436}.
    General information above from UniProt

    IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they also increase the ability of uninfected host cells to resist new infection by virus.Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities.

    IFN-alpha / IFNA1 / IFN Alternative Name

    IFL,IFN,IFNA@,IFNA13,IFN-ALPHA,IFN-alphaD, [homo-sapiens]
    IFL,IFN,IFNA@,IFN-ALPHA,IFN-alpha 1b,IFN-alpha-1/13,IFN-alphaD,interferon alpha 1b,interferon alpha-1/13,interferon alpha-D,interferon-alpha1,leIF D,MGC138207,MGC138505,MGC138507,IFNA13, [human]
    Ifa1,IFN-alpha-1,interferon alpha family gene 1,interferon alpha-1,RP23-360M23.1, [mouse]
    Ifa1, [mus-musculus]

    IFN-alpha / IFNA1 / IFN Related Studies

  • Takayama I, et al. (2012) The nucleocapsid protein of measles virus blocks host interferon response. Virology. 424(1):45-55.
  • Vairo D, et al. (2011) Severe impairment of IFN-? and IFN-? responses in cells of a patient with a novel STAT1 splicing mutation. Blood. 118(7):1806-17.
  • Bhattacharya S, et al. (2011) Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFN? via accelerating the degradation of its receptor. Blood. 118(15):4179-87.
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