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CD48/Blast-1  Protein, Antibody, ELISA Kit, cDNA Clone

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Expression host: Human Cells  
10797-H08H-50
10797-H08H-100
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100 µg 
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Expression host: Human Cells  
10797-H02H-50
10797-H02H-100
50 µg 
100 µg 
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Description: Active  
Expression host: Human Cells  
50415-M08H-50
50415-M08H-100
50 µg 
100 µg 
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Expression host: Human Cells  
50415-M02H-50
50415-M02H-100
50 µg 
100 µg 
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  • Slide 1
Expression host: Human Cells  
80286-R08H-50
80286-R08H-100
50 µg 
100 µg 
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Expression host: Human Cells  
80286-R02H-50
80286-R02H-100
50 µg 
100 µg 
Add to Cart
  • Slide 1

CD48/Blast-1 Related Area

CD48/Blast-1 Related Pathways

    CD48/Blast-1 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    CD48/Blast-1 Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    CD48/Blast-1 Summary & Protein Information

    CD48/Blast-1 Background

    Subunit structure: Interacts with CD244 in an heterophilic manner. {ECO:0000250}.
    Subcellular location: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
    Sequence similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. {ECO:0000305}.; Contains 1 Ig-like V-type (immunoglobulin-like) domain. {ECO:0000305}.
    General information above from UniProt

    Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.

    CD48/Blast-1 Alternative Name

    BCM1,BLAST,hCD48,mCD48,BLAST1,SLAMF2,MEM-102, [homo-sapiens]
    Blast-1, [Human]
    AI449234,AW610730,BCM1,Bcm-1,BLAST,BLAST1,BLAST-1,Cd48,MEM-102,Sgp-60,SLAMF2, [mouse]
    BCM1,BLAST,Bcm-1,BLAST1,SLAMF2,Sgp-60,BLAST-1,MEM-102,AI449234,AW610730, [mus-musculus]

    CD48/Blast-1 Related Studies

  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"