Quick Order

Home>CD160
Text Size:AAA

CD160/NK1/BY55  Protein, Antibody, ELISA Kit, cDNA Clone

Expression host: Human Cells  
12191-H08H-50
12191-H08H-100
50 µg 
100 µg 
Add to Cart
  • Slide 1
Expression host: Human Cells  
50805-M02H-50
50805-M02H-200
50 µg 
200 µg 
Add to Cart
  • Slide 1
Expression host: Human Cells  
90224-C08H-50
90224-C08H-100
50 µg 
100 µg 
Add to Cart
  • Slide 1
Expression host: Human Cells  
90224-C02H-50
90224-C02H-100
50 µg 
100 µg 
Add to Cart
  • Slide 1
Expression host: Human Cells  
90224-CCCH-50
90224-CCCH-100
50 µg 
100 µg 
Add to Cart
  • Slide 1

CD160/NK1/BY55 Related Area

CD160/NK1/BY55 Related Pathways

    CD160/NK1/BY55 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    CD160/NK1/BY55 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    Featured Reagent Products

    CD160/NK1/BY55 Summary & Protein Information

    CD160/NK1/BY55 Background

    Subunit structure: Homomultimer; disulfide-linked.
    Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
    Tissue specificity: Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.
    Sequence similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. {ECO:0000305}.
    General information above from UniProt

    CD160 antigen, also known as Natural killer cell receptor BY55 and CD160, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and small intestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymphocytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD160+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.

    CD160/NK1/BY55 Alternative Name

    NK1,BY55,NK28, [homo-sapiens]
    BY55,NK1,NK28,RP11-373C9.1,CD160,FLJ46513, [human]
    AU045688,By55,Cd160, [mouse]
    By55,AU045688, [mus-musculus]

    CD160/NK1/BY55 Related Studies

  • Barakonyi A. et al., 2004, J Immunol.173 (9): 5349-54.
  • Rabot M. et al., 2006, Transpl Immunol. 17 (1): 36-8.
  • Abecassis S. et al., 2007, J Invest Dermatol. 127?(5): 1161-6.
  • Giustiniani J.?et al., 2007, J Immunol. 178 (3): 1293-300.
  • Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"