Quick Order

Home>C1R
Text Size:AAA

C1R  Protein, Antibody, ELISA Kit, cDNA Clone

C1R Related Area

C1R Related Protein, Antibody, cDNA Gene, and ELISA Kits

C1R Related Protein, Antibody, cDNA Gene, and ELISA Kits

Featured Reagent Products

C1R Summary & Protein Information

C1R Background

Catalytic activity: Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent C1s to form the active form of C1s (EC 3.4.21.42).
Subunit structure: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
Post-translational: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. {ECO:0000269|PubMed:2820791}.
Sequence similarity: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE-ProRule:PRU00274}.; Contains 2 CUB domains. {ECO:0000255|PROSITE-ProRule:PRU00059}.; Contains 1 EGF-like domain. {ECO:0000305}.; Contains 1 peptidase S1 domain. {ECO:0000255|PROSITE-ProRule:PRU00274}.; Contains 2 Sushi (CCP/SCR) domains. {ECO:0000255|PROSITE-ProRule:PRU00302}.
General information above from UniProt

C1R Alternative Name

C1R Related Studies

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"