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C1QC  Protein, Antibody, ELISA Kit, cDNA Clone

C1QC Related Area

C1QC Related Pathways

    C1QC Related Protein, Antibody, cDNA Gene, and ELISA Kits

    C1QC Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    C1QC Summary & Protein Information

    C1QC Background

    Subunit structure: C1 is a calcium-dependent trimolecular complex of C1q, R and S in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.
    Subcellular location: Secreted.
    Post-translational: O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups.
    Involvement in disease: DISEASE: Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. {ECO:0000269|PubMed:8630118}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Sequence similarity: Contains 1 C1q domain. {ECO:0000255|PROSITE-ProRule:PRU00368}.; Contains 1 collagen-like domain. {ECO:0000305}.
    General information above from UniProt

    C1QC Alternative Name

    C1QG,C1Q-C, [homo-sapiens]
    C1Q-C,C1QG, [Human]
    AI385742,C1qg,Ciqc, [Mouse]
    C1qg,Ciqc,AI385742, [mus-musculus]

    C1QC Related Studies

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