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VISTA/GI24/B7-H5  Protein, Antibody, ELISA Kit, cDNA Clone

Expression host: Human Cells  
13482-H02H-50
13482-H02H-100
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Expression host: Human Cells  
13482-H08H-50
13482-H08H-100
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100 µg 
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Expression host: Human Cells  
51550-M02H-50
51550-M02H-200
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200 µg 
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Expression host: Human Cells  
51550-M08H-50
51550-M08H-200
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200 µg 
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Expression host: Human Cells  
81347-R02H-50
81347-R02H-200
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Expression host: Human Cells  
90844-C08H-50
90844-C08H-200
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Expression host: Human Cells  
90801-K08H-50
90801-K08H-200
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200 µg 
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Expression host: Human Cells  
90801-K02H-50
90801-K02H-200
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200 µg 
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VISTA/GI24/B7-H5 Related Area

VISTA/GI24/B7-H5 Related Pathways

    VISTA/GI24/B7-H5 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    VISTA/GI24/B7-H5 Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    VISTA/GI24/B7-H5 Summary & Protein Information

    VISTA/GI24/B7-H5 Background

    Subcellular location: Cell membrane {ECO:0000269|PubMed:20666777}; Single-pass type I membrane protein {ECO:0000269|PubMed:20666777}.
    Post-translational: At the cell surface, may be cleaved by MMP14. {ECO:0000269|PubMed:20666777}.
    Sequence similarity: Contains 1 Ig-like (immunoglobulin-like) domain. {ECO:0000305}.
    General information above from UniProt

    C10orf54, also known as GI24, belongs to the immunoglobulin superfamily. It is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESCs, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, C10orf54 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

    VISTA/GI24/B7-H5 Alternative Name

    B7H5,B7-H5,GI24,platelet receptor Gi24,PP2135,RP11-472K8.3,SISP1,stress induced secreted protein 1, [human]

    VISTA/GI24/B7-H5 Related Studies

  • Ota T, et al. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 36(1):40-5.
  • Deloukas P, et al. (2004) The DNA sequence and comparative analysis of human chromosome 10. Nature. 429(6990):375-81.
  • Colland F, et al. (2004) Functional proteomics mapping of a human signaling pathway. Genome Res. 14(7):1324-32.
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